According to the docs:
Filters defined during configuration cannot be removed when viewing the report, but can be disabled/enabled by users viewing the report.
However I just made a report with two filters defined in configuration, and my user sees the filters, but they say they can’t disable them. (I don’t have an easy way to test this, because as an admin, I can’t see what a user would see - which is its own issue!) The user is a Member with Editor access to the entire Space.
So my report doesn’t work at all, because I defined two mutually-exclusive filters (current month and prior month) and since they’re both enabled all the data is filtered out.
My workaround was to remove the global filters and have the user reconfigure them in their personal view, but that means all other users have to do the same thing.